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Publications
(24.) Piña, J.; Aguirre, L. S.; Litwiller, L. T.; Ly, H.; Crockett, M. P.; Thomas, A. A. "Development of a Highly Selective Synthesis of 4-Substituted Tetrahydroquinolines: Substrate Scope and Mechanistic Study". Pre-print available on ChemRxiv 2024. DOI:10.26434/chemrxiv-2024-rbbcl
(23.) Hsu, H.-H.; Chen, C.-C.; Kang, S.; Sk, M. R.; Thomas, A. A. "Functionalization of Pyridines at Remote Synthetic Landscapes via Undirected Metalation and Capture". Pre-print available on ChemRxiv 2024. DOI: 10.26434/chemrxiv-2024-g6nk9
(22.) Gonzalez, R. M.; Hsu, H.-H.; Thomas, A. A. "Preparation of Highly Reactive Lithium Metal Dendrites and the Synthesis of (Trimethylsilyl)methyllithium". Org. Synth. 2024, 101, 342-365. DOI: 10.15227/orgsyn.101.0342
(21.) Wu, D.; Martin, R. T.; Piña, J.; Kwon, J.; Crockett, M. P.; Thomas, A. A.; Gutierrez, O.; Park, N. H.; Hedrick, J. L.; Campos, L. M. “Cyclopropenimine-Mediated CO2 Activation for the Synthesis of Polyurethanes and Small-Molecule Carbonates and Carbamates.”. Angew. Chem., Int. Ed. 2024, 63, e20240128.
(20.) Aguirre, L. S.; Litwiller, L. T.; Lugo, A. N.; Thomas, A. A. “Design and Synthesis of Dialkylarylphosphine Urea Ligands and their Application in Palladium-Catalyzed Cross-Coupling Reactions”. Helv. Chim. Acta. 2024, 107, e202300244.
(19.) Arriaga, D. K.; Kang, S.; Thomas, A. A. "Solvent Effects on the Rate of Ozonolysis: Development of a Homogeneous Flow Ozonolysis Protocol”. J. Org. Chem. 2023, 88, 13720–13726.
- Preprint available on ChemRxiv 2023. DOI: 10.26434/chemrxiv-2023-sz64b
- Featured in "Some Items of Interest to Process R&D Chemists and Engineers" Org. Process Res. Dev. 2023.
- Featured in "Investigating Ozone Solubility in Organic Solvents for Use in Flow Ozonolysis Protocols" Synfacts 2023, 19, 1279.
(18.) Arriaga, D. K.; Thomas, A. A. "Capturing primary ozonides for a syn-dihydroxylation of olefins". Nat. Chem. 2023, 15, 1262-1266.
- Preprint available on ChemRxiv 2022. DOI: 10.26434/chemrxiv-2022-hs9lp
- Featured in "Some Items of Interest to Process R&D Chemists and Engineers" Org. Process Res. Dev. 2023, 27, 1535-1545.
- Trauner, D.; Zott M. D. "Transition Metal-Free syn-Dihydroxylation via Interrupted Ozonolysis" Synfacts 2023, 19, 1043.
- Featured in "festphasen- und flowsynthese" (solid phase and flow synthesis) section "Trendbericht Organische Chemie 2024" Nachr. Chem. 2024, 72, 44-67.
(17.) Crockett, M. P.; Piña, J.; Gogoi, A. R.; Lalisse, R. F.; Nguyen, A. V.; Gutierrez, O.; Thomas, A. A. "Breaking the tert-Butyllithium Contact Ion Pair: A Gateway to Alternate Selectivity in Lithiation Reactions". J. Am. Chem. Soc. 2023, 145, 10743–10755.
- Preprint available on ChemRxiv 2022. DOI: 10.26434/chemrxiv-2022-z6c5h
(16.) Crockett, M. P.; Aguirre, L. S.; Jimenez, L. B.; Hsu, H.-H.; Thomas, A. A. "Preparation of Highly Reactive Lithium Metal Dendrites for the Synthesis of Organolithium Reagents". J. Am. Chem. Soc. 2022, 144, 16631-16637.
- Preprint available on ChemRxiv 2022. DOI: 10.26434/chemrxiv-2022-k1pvr
- Spotlights on Recent JACS Publications: Reagent Shortage Leads to a Better Alternative
- C&EN Article: "New form of lithium reacts 20 times as fast as powdered metal"
- ChemistryViews Article: "Lithium Metal Dendrites as a Highly Reactive Lithium Source"
- Featured in "Trendbericht Anorganische Chemie 2023: Hauptgruppen" Nachr. Chem. 2023, 71, 46-57.
(15.) Arriaga, D. K.; Thomas, A. A. "Antibiotics the easy way". Nat. Synth. 2022 (News & Views).
Prior to independent career
(14.) Zhukhovitskiy, A. V.; Kobylianskii, I. J.; Thomas, A. A.; Evans, A. M.; Delaney, C. P.; Flanders, N. C.; Denmark, S. E.; Dichtel, W. R.; Toste, F. D. "A Dinuclear Mechanism Implicated in Controlled Carbene Polymerization". J. Am. Chem. Soc. 2019, 141, 6473-6478.
(13.) Thomas, A. A.; Speck, K.; Kevlishvili, I.; Lu, Z.; Liu, P.; Buchwald, S. L. "Mechanistically Guided Design of Ligands That Significantly Improve the Efficiency of CuH-Catalyzed Hydroamination Reactions". J. Am. Chem. Soc. 2018, 140, 13976- 13984.
(12.) Thomas, A. A.; Zahrt, A. F.; Delaney, C. P.; Denmark, S. E. "Elucidating the Role of the Boronic Esters in the Suzuki-Miyaura Reaction: Structural, Kinetic, and Computational Investigations". J. Am. Chem. Soc. 2018, 140, 4401-4416.
(11.) Thomas, A. A.; Denmark, S. E. Ernest L. Eliel, "A Physical Organic Chemist with the Right Tool for the Job: Rapid Injection Nuclear Magnetic Resonance". In Stereochemistry and Global Connectivity: The Legacy of Ernest Eliel; Cheng, H. N., Ed.; ACS Symposium Series; American Chemical Society: Washington, DC, 2017; Vol. 2, pp 105-134.
(10.) Thomas, A. A.; Wang, H.; Zahrt, A. F.; Denmark, S. E. "Structural, Kinetic, and Computational Characterization of the Elusive Arylpalladium(II)boronate Complexes in the Suzuki-Miyaura Reaction". J. Am. Chem. Soc. 2017, 139, 3805-3821.
(9.) Thomas, A. A.; Denmark, S. E. "Pre-transmetalation intermediates in the Suzuki-Miyaura reaction revealed: The missing link". Science, 2016, 352, 329-332.
(8.) Dale, J. E.; Vermeulen, N. A.; Thomas, A. A.; Barnes, J. C.; Juríček, M.; Blackburn, A. K.; Strutt, N. L.; Sarjeant, A. A.; Stern, C. L.; Denmark, S. E.; Stoddart, J. F. "ExCage". J. Am. Chem. Soc. 2014, 136, 10669-10682.
(7.) Bertz, S. H.; Cope, S. K.; Hardin, R. A.; Murphy, M. D.; Ogle, C. A.; Smith, D. T.; Thomas, A. A.; Whaley, T. N. "Complexes of the Gilman Reagent with Double Bonds across the π−σ Continuum". Organometallics. 2012, 31, 7827-7838.
(6.) Bertz, S. H.; Browder, K. L.; Hardin, R. A.; Murphy M. D., Ogle, C. A.; Thomas, A. A. "Ligand Exchange in Mixed Organocuprate(I) π-Complexes." Organometallics. 2012, 31, 7809-7811.
(5.) Bertz, S. H.; Hardin, R. A., Murphy, M. D., Ogle, C. A., Richter, J. D., Thomas, A. A. "Rapid Injection NMR Reveals η3 ‘π−Allyl’ CuIII Intermediates in Addition Reactions of Organocuprate Reagents". J. Am. Chem. Soc. 2012. 134, 9557-9560.
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(4.) Bertz, S. H.; Hardin, H. A.; Murphy, M. D.; Ogle, C. A.; Richter, J. D.; Thomas, A. A. "Minimization of Organocuprate Complexity through Self-Organization: Remarkable Orientation Effect in Mixed Cuprate π Complexes". Angew. Chem. Int. Ed. 2012, 51, 2681-2685.
(3.) Bertz, S. H.; Moazami, Y.; Murphy, M. D.; Ogle, C. A.; Richter, J. D.; Thomas, A. A. "Complexes of Gilman Reagents with C−S and C−N Double Bonds: σ or π Bonding"? J. Am. Chem. Soc. 2010, 132, 9549-9551.
(2.) Bertz, S. H.; Murphy, M. D.; Ogle, C. A.; Thomas, A. A. "Organocuprate(III) chemistry: synthesis and reactivity of amido, cyano, phosphido and thiolato ate complexes of copper(III)". Chem. Commun. 2010, 46, 1255-1256.
(1.) Bartholomew, E. R.; Bertz, S. H.; Cope, S. K.; Murphy, M. D.; Ogle, C. A.; Thomas, A. A. "Serendipity strikes again–efficient preparation of lithium tetramethylcuprate(III) via rapid injection NMR". Chem. Commun. 2010, 46, 1253-1254.
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